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Clinical Neurobiology Laboratory

Stress research

Eberhard Fuchs


Stress research

 

Stressful life events are among the most potent factors that trigger or induce depressive episodes in humans.
The stress hypothesis of mood disorders has stimulated the development of animal models of depression.
Animal models are invaluable in human psychopathology preclinical research. Valid animal models, used to study the pathophysiology of depression and specific biological and behavioral responses to antidepressant drug treatments, are of prime interest.

In recent years, we could demonstrate that chronic psychosocial stress in a non-rodent species, the male tree shrew (Tupaia belangeri), represents a natural and valid paradigm for studying the behavioral, endocrine, and neurobiological changes that may underlie stress-related disorders such as major depression.

 
© 09.01.12  Clinical Neurobiology Laboratory
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