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Clinical Neurobiology Laboratory

Parkinson's disease

Enrique Garea Rodriguez


Marmoset model of Parkinson's disease



A common marmoset monkey (Callithrix jacchus)
performing a behavioural task to assess
sensori-motor control

 

Parkinson's disease (PD) is a strongly invalidating neurological disorder produced by the degeneration of dopaminergic neurons in the mid brain. Despite its high prevalence in the occidental world and its irreversible prognosis, no pharmacological or surgical treatment has provided long term remission of motor and cognitive symptomatology in PD patients. Therefore, a primate model of this illness to test new treatment strategies at a pre-clinical level is highly needed. In our model neuropsychological and psychomotor functions are assessed. Motor disturbances are measured using automated devices and standardized tests are used to assess fine motor abilities. High level cognitive functions like attention and memory are evaluated using the CANTAB system.

 

Techniques: 
Motor control and neuropsychological test batteries (CANTAB)

 
© 09.01.12  Clinical Neurobiology Laboratory
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