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Clinical Neurobiology Laboratory

Tree shrews

Tree shrews



 

The German Primate Center is breeding and housing tree shrews (Tupaia belangeri; see Fuchs, UFAW Handbook, 1999). In preclinical biomedical research, this species represents a valuable animal model whenever a small omnivorous non-rodent species is desired. Tree shrews can be used in many fields of preclinical research such as neuropharmacology and virology.

Male tree shrews are used as social stress model because of their pronounced territorial behavior. When living in visual and olfactory contact with a dominant male by which it has been defeated, a subordinate tree shrew shows typical stress symptoms with respect to behavioral, physiological and neuroendocrine parameters. It is an interesting aspect of preclinical research that many of the alterations in subordinate tree shrews are similar to the symptoms observed in depressed patients.


Read more about the chronic psychosocial stress model in
Fuchs and Flügge, Pharm Biochem Behav (2002).

Fuchs, CNS Spectrum 10:182-189 (2005)

 
© 09.01.12  Clinical Neurobiology Laboratory
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